Dual-fluorescent RNA probe with extremely
large stokes shifts.
A. Kobori, T. Ueda,
Y. Sanada, A. Yamayoshi, A. Murakami.
Biosci. Biotechnol. Biochem. 2013, in
press.
Structural imsight for design of inhibitors against RISC function
A. Yamayoshi, Y.
Yamada, A. Kobori, A. Murakami.
Chem. Lett. 41, 1684-1685, 2012.
Novel photoresponsive cross-linking oligodeoxyribonucleotides having a caged a-chloroaldehyde.
A.
Kobori, T. Yamauchi, Y. Nagae, A. Yamayoshi, A. Murakami.
Bioorg. Med.Chem., 20,
5071-5076, 2012.
RNA-based diagnosis in a multicellular
specimen by whole mount in situ hybridization using an RNA-specific probe.
T. Ueda, A.
Kobori, A. Yamayoshi, H. Yoshida, M. Yamaguchi, A. Murakami.
Bioorg. Med. Chem., 20, 6034-6039, 2012.
Synthesis and Crosslinking Activity of
4-N-(4,5’,8-Trimethylpsoralen-4’-ylmethyl)-
2’-deoxycytidine-containing Oligodeoxyribonucleotides.
A. Kobori, T. Kohji, Y. Nagae, A.
Yamayoshi, A. Murakami.
Chem. Lett., 41, 804-805, 2012.
Surprising Repair Activities of Nonpolar Analogs of 8-oxoG Expose Features
of Recognition and Catalysis by Base Excision Repair Glycosylases.
P. L. McKibbin, A. Kobori, Y. Taniguchi, E. T. Kool, S. S. David.
J. Am. Chem. Soc., 134, 1653-1661, 2012.
Real-time Imaging of RNA Expression in
Living Cells Using Bispyrene-modified RNA Probes.
R. Waki,
A. Yamayoshi, A. Kobori, A. Murakami.
Chem. Lett., 40, 1247-1248, 2011.
Decoy-DNA Against Special AT-Rich Sequence Binding Protein 1 Inhibits the
Growth and Invasive Ability of Human Breast Cancer.
A.
Yamayoshi, M. Yasuhara, S. Galande, A. Kobori, A. Murakami.
Oligonucleotides, 21, 115-121, 2011.
Development of a system to sensitively and specifically visualize-fos mRNA in
living cells using bispyrene-modified RNA probes.
Waki R.,
Yamayoshi A., Kobori A., Murakami A.
Chem. Commun., 47, 4204-4206, 2011.
Specific regulation of point-mutated K-ras-immortalized cell proliferation
by a photo-dynamic antinsense strategy..
M. Higuchi; A. Yamayoshi; K. Kato; A. Kobori; N. Wake; A. Murakami.
Oligonucleotides,20, 37-4,. 2010.
Sequence selective formation of 1, N6-ethenoadenine in DNA by
furan-conjugated probe.
A. Kobori; J. Morita; M. Ikeda; A. Yamayoshi; A. Murakami.
Bioorg. Med. Chem. Lett. 19, 3657-3660, 2009.
Synthesis and Photoinduced Cross-linking Reactions of
4,5',8-Trimethylpsoralen-incorporated Oligodeoxyribonucleotide.
A. Kobori; K. Takaya; M. Higuchi; A. Yamayoshi; A. Murakami.
Chem.Lett., 38, 272-273, 2009.
Synthesis of antisense oligonucleotides containing
2'-O-psoralenylmethoxyalkyl adenosine for photodynamic regulation of point
mutations in RNA.
M. Higuchi; A. Kobori; A. Yamayoshi; A. Murakami.
Bioorg. Med. Chem, 17, 475-48,. 2009.
Dimer of 2,7-Diamino-1,8-naphthyridine for the Detection of Mismatches
Formed by Pyrimidine Nucleotide Bases.
A. Kobori; and K. Nakatani.
Bioorg. Med. Chem. 16, 10338-10344, 2008.
Efficient synthesis of functionalized oligodeoxyribonucleotides with
base-labile groups using a new silyl linker.
A. Ohkubo; R. Kasuya; K. Aoki; A. Kobori; H. Taguchi; K. Seio; M.Sekine.
Bioorg. Med. Chem. 16, 5345-5351, 2008.
Microarray-based label-free detection of RNA using bispyrene-modified
2′-O-methyl oligoribonucleotide as capture and detection probe.
Sakamoto, T., Kobori, A., Murakami, A.
Bioorg. Med. Chem. Lett.,18,2590-2593, 2008
Naphthyridine-tethered oligodeoxynucleotides: Dye/DNA conjugates for
homogeneous SNPs assays.
Kobori, A., Mori, T., Ubayashi, M., Murakami. A.
Chem. Lett. 37, 354-355, 2008
Detection of L-DNA-tagged PCR products by surface plasmon resonance imaging.
Hayashi, G., M. Hagihara, M., Kobori, A., Nakatani, K.
Chembiochem, 22, 169-171, 2007
Allele Specific C-Bulge Probes with One Unique Fluorescent Molecule
Discriminate the Single Nucleotide Polymorphism in DNA.
Takei, F., Suda, H., Hagihara, M., Zhang, J., Kobori, A., Nakatani, K.
Chemistry - A European Journal, 13, 4452-4457, 2007
Selective Photo-Cross-Linking of 2'-O-Psoralen-Conjugated Oligonucleotide
with Rnas Having Point Mutations.
Higuchi, M., Yamayoshi, A., Yamaguchi, T., Iwase, R., Yamaoka, T., Kobori, A.,
Murakami, A.
nucleosides, nucleotides, nucleic acids, 26, 277-290, 2007
Analysis of mismatched DNA by mismatch binding ligand (MBL)?Sepharose
affinity chromatography.
Goto, Y., Suda, H., Kobori, A., Nakatani, K.
Anal. Bioanal. Chem., 388, 1165-1173, 2007
Conformational studies of 4-N-carbamoyldeoxycytidine derivatives and
synthesis and hybridization properties of oligodeoxyribonucleotides
incorporating these modified bases.
Miyata, K., Kobori, A., Tamamushi, R., Ohkubo, A., Taguchi, H., Seio, K.,
Sekine, M.
Eur. J. Org. Chem., 16, 3626-3637, 2006
Evaluation of mismatch-binding ligands as inhibitors for Rev-RRE
interaction.
K. Nakatani; S. Horie; Y. Goto; A. Kobori; S. Hagihara.
Bioorg. Med. Chem., 14, 5384-5388, 2006
Small-molecule ligand induces nucleotide flipping in (CAG)n trinucleotide
repeats.
K. Nakatani; S. Hagihara; Y. Goto; A. Kobori; M. Hagihara; G. Hayashi; M. Kyo;
M. Nomura; M. Mishima; C. Kojima.
Nature Chemical Biology, 1, 39-43, 2005
A new ligand binding to G?G mismatch having improved thermal and alkaline
stability.
T. Peng; T. Murase; Y. Goto; A. Kobori; K. Nakatani.
Bioorg. Med. Chem. Lett. , 15, 259-262, 2005
N,N'-Bis(3-aminopropyl)-2,7-diamino-1,8-naphthyridine stabilized a single
pyrimidine bulge in duplex DNA.
H. Suda; A. Kobori; J. Zhang; G. Hayashi; K. Nakatani.
Bioorg. Med. Chem., 13, 4507-4512, 2005
2-Ureidoquinoline : a useful molecular element for stabilizing single
cytosine and thymine bulges.
A. Kobori; T. Murase; H. Suda; I. Saito; K. Nakatani.
Bioorg. Med. Chem. Lett., 14, 3431-3433, 2004
The Binding of Guanine-Guanine Mismatched DNA to Naphthyridine Dimer
Immobilized Sensor Surfaces: Kinetic Aspects.
K. Nakatani; A. Kobori; H. Kumasawa; Y. Goto; I. Saito.
Bioorg. Med. Chem., 12, 3117-3123, 2004
The SPR sensor Detection Cytosine-Cytosine mismatches.
A. Kobori; S. Horie; H. Suda; I. Saito; K. Nakatani.
J. Am. Chem. Soc., 32, 278-286, 2004
Detection of guanine-adenine mismatches by surface plasmon resonance sensor
carrying naphthyridine-azaquinolone hybrid on the surface.
S. Hagihara; H. Kumasawa; Y. Goto; G. Hayashi; A. Kobori; K. Nakatani.
Nucleic Acids Res., 32, 278-286, 2004
Highly sensitive detection of GG mismatched DNA by surfaces immobilized
naphthyridine dimer through poly(ethylene oxide) linker.
K. Nakatani; A. Kobori; H. Kumasawa; I. Saito.
Bioorg. Med. Chem. Lett., 14, 1105, 2007
Unique participation of unprotected internucleotidic phosphodiester residues
on unexpected cleavage reaction of the Si - O bond of the diisopropylsilandiyl
group used as a linker for the solid-phase synthesis of 5'-terminal guanylated
oligodeoxynucleotides.
M. Ushioda; M. Kadokura; T. Moriguchi; A. Kobori; M. Aoyagi; K. Seio; M. Sekine.
Helv. Chim. Acta, 85, 2930-2945, 2002
A new silyl ether-type linker useful for the automated synthesis of
oligonucleotides having base-labile protective groups.
A. Kobori; K. Miyata; M. Ushioda; K. Seio; M. Sekine.
Chem. Lett., 1, 16-17, 2002
A New Method for the Synthesis of Oligodeoxyribonucleotides Containing
4-N-Alkoxycarbonyldeoxycytidine Derivatives and Their Hybridization Properties.
A. Kobori; K. Miyata; M. Ushioda; K. Seio; M. Sekine.
J. Org. Chem.,67, 476-485, 2002
Synthesis and hybridization ability of oligodeoxyribonucleotides
incorporating N-acyldeoxycytidine derivatives.
T. Wada; A. Kobori; S. Kawahara; M. Sekine.
Eur. J. Org. Chem.,4583-4593, 2001
Theoretical study of the hydrogen bond energy of base pairs formed between
substituted 1-methylcytosine derivatives and 9-methylguanine.
S. Kawahara; A. Kobori; M. Sekine; K. Taira; T. Uchimaru.
J. Phys. Chem. A, 105, 10596-10601, 2001
Synthesis and properties of oligodeoxyribonucleotides containing
4-N-acetylcytosine bases.
T. Wada; A. Kobori; S. Kawahara; M. Sekine.
Tetrahedron Lett., 39, 6907-6910, 1998